TABLE 1

Scintigraphic and Histopathologic Findings in Patients with Tumor Localized in Head and Neck Region

Patient no.	Age (y)	Sex	Tumor type and location	Planar imaging*					Localization of nodes seen on planar imaging	SPECT/CT imaging				Surgical and histopathologic results
Patient no.	Age (y)	Sex	Tumor type and location					First nodes detected	Localization of nodes seen on planar imaging	Additional nodes	Single vs. multiple basins	Additional nodes^†	Single vs. multiple basins	Surgical and histopathologic results	Clinically relevant added value^‡
1	70	M	SCC, tongue	Midjugular	Supraclavicular	Unclear	Mid- and lower jugular chain	+ jugulo-digastric (hidden)	Multiple	+	Positive SN (cervical)
2	50	F	SCC, tongue	High jugular	4 along jugular chain	Single	Jugular chain	+ submental (hidden)	Single	+	Negative
3	43	M	SCC, tongue	High jugular	1 midjugular	Single	Jugular chain	−	Single	−	Positive SN (cervical)
4	72	M	SCC, tongue	Supraclavicular, suspected submandibular	−	Unclear	Supraclavicular	Second node was ruled out (injection site)	Single	+	Positive SN (supraclavicular)
5	27	M	SCC, tongue	High jugular	3 along jugular chain	Single	Jugular chain	+ posterior cervical triangle	Multiple	+	Multiple involved nodes
6	54	M	SCC, oral mucosa	High jugular	4 along jugular chain	Single	Jugular chain	−	Single	−	Negative
7	81	M	MM, head	2 preauricular	2 submandibular	Unclear	2 preauricular, 1 submandibular, 1 jugulodigastric	−	Unclear	−	Negative
8	67	M	MM, scalp	Faint occipital	−	Single	Posterior cervical triangle	−	Single	−	Multiple involved nodes
9	55	M	MM, scalp	High jugular, contralateral occipital	1 cervical	Multiple	2 jugular, 2 contralateral occipital	−	Multiple	−	Negative

↵* Including images obtained with ⁵⁷Co flood source.
↵^† Additional nodes detected on SPECT/CT only. Hidden = hidden by scatter radiation of injection site.
↵^‡ SPECT/CT added data were considered clinically relevant if they guided surgeon to SNs that were undetected on planar images or to SNs in another basin.
MM = malignant melanoma.