Comparison of CBF, V0, and Other Parametric Values (Mean ± SD) in the 2 Patient Groups
Parameter | Group A (n = 8) | Group B (n = 8) | ||||
---|---|---|---|---|---|---|
Ipsilateral | Contralateral | Ipsilateral | Contralateral | |||
CBF (mL/min/100 g) | ||||||
Baseline | 36.4 ± 10.9* | 43.0 ± 8.7 | 35.9 ± 4.7† | 40.5 ± 6.7 | ||
ACZ | 34.9 ± 11.1* | 55.0 ± 8.9‡ | 46.9 ± 4.9*,‡ | 56.2 ± 8.5‡ | ||
% Change | −4.1 ± 12.0* | 29.9 ± 18.3 | 32.2 ± 8.2 | 39.6 ± 12.7 | ||
V0 (mL/100 g) | ||||||
Baseline | 1.56 ± 0.42† | 1.85 ± 0.46 | 1.70 ± 0.53* | 2.04 ± 0.40 | ||
ACZ | 1.90 ± 0.41†,§ | 2.90 ± 0.97‡ | 2.40 ± 0.70*,‡ | 3.12 ± 0.45‡ | ||
% Change | 25.0 ± 25.3* | 55.6 ± 30.2 | 44.0 ± 24.2† | 55.8 ± 22.1 | ||
CMRo2 (mL/min/100 g) | 2.70 ± 0.48 | 2.92 ± 0.32 | 2.82 ± 0.29* | 3.15 ± 0.39 | ||
OEF (%) | 51.3 ± 7.5* | 46.7 ± 6.2 | 48.5 ± 4.9 | 47.7 ± 5.8 | ||
CBV (mL/100 g) | 4.65 ± 0.31† | 4.17 ± 0.57 | 4.09 ± 0.29 | 3.88 ± 0.32 |
↵* P < 0.01 comparing right and left hemispheres (repeated-measures ANOVA with paired t test).
↵ † P < 0.05 comparing right and left hemispheres (repeated-measures ANOVA with paired t test).
↵ ‡ P < 0.005 comparing the 2 conditions of baseline and ACZ injection (repeated-measures ANOVA with paired t test).
↵ § P < 0.05 comparing the 2 conditions of baseline and ACZ injection (repeated-measures ANOVA with paired t test).