Patient no. | Sex | Age (y) | Disease duration (y) | HYS | Clinical manifestations | Visual inspection | SUR | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PET | SPECT | ||||||||||||||||||||||
ST | PU | ST | PU | ||||||||||||||||||||
18F-FDOPA PET | 99mTc-TRODAT-1 SPECT | R | L | R | L | R | L | R | L | ||||||||||||||
1 | M | 78 | 3 | I | Bradykinesia, tremor, R limbs | Mildly decreased uptake in bil. ST | Decreased uptake in bil. PU, more on L | 1.31 | 1.36 | 1.42 | 1.5 | 1.63 | 1.25 | 1.49 | 1.04 | ||||||||
2 | F | 48 | 5 | III | Rigidity, akinesia, tremor, bil. | Decreased uptake in bil. PU, more on R | Decreased uptake in bil. PU, more on R | 0.70 | 0.80 | 0.27 | 0.35 | 1.08 | 1.01 | 0.75 | 0.78 | ||||||||
3 | M | 59 | 8 | IV | Rigidity, akinesia, tremor, bil. | Decreased uptake in bil. ST, more on R | Markedly decreased uptake in bil. ST, more on R | 0.44 | 0.47 | 0.41 | 0.53 | 0.37 | 0.89 | 0.25 | 0.65 | ||||||||
4 | F | 66 | 9 | IV | Rigidity, akinesia, tremor, bil. | No uptake in bil. PU | Markedly decreased uptake in bil. ST, more on L | 0.61 | 0.72 | 0.48 | 0.58 | 0.78 | 0.50 | 0.74 | 0.31 | ||||||||
5 | M | 67 | 12 | III | Rigidity, akinesia, tremor, bil. | Decreased uptake in bil. CA, no uptake in bil. PU | Decreased uptake in bil. ST, more on L | 0.45 | 0.40 | 0.42 | 0.36 | 0.97 | 0.38 | 0.78 | 0.51 | ||||||||
6 | M | 66 | 7 | IV | Rigidity, akinesia, tremor, bil. | Decreased uptake in bil. PU and L CA | Decreased uptake in bil. PU and L CA | 0.36 | 0.34 | 0.41 | 0.34 | 1.13 | 0.86 | 0.82 | 0.63 | ||||||||
7 | M | 77 | 6 | III | Rigidity, akinesia, tremor, bil. | Decreased uptake in bil. ST | Decreased uptake in bil. ST, more on R | 0.67 | 0.62 | 0.76 | 0.79 | 0.82 | 0.98 | 0.66 | 0.93 | ||||||||
8 | M | 69 | 7 | II | Rigidity, tremor, R > L limbs | Decreased uptake in bil. PU, more on L | Decreased uptake in bil. PU, more on L | 0.50 | 0.51 | 0.78 | 0.72 | 0.96 | 0.95 | 0.67 | 0.45 | ||||||||
9 | F | 70 | 5 | III | Rigidity, tremor, R > L limbs | Decreased uptake in bil. ST, more on L | Decreased uptake in bil. ST, more on L | 0.84 | 0.73 | 0.87 | 0.74 | 1.17 | 0.43 | 1.06 | 0.02 | ||||||||
10 | F | 67 | 4 | III | Rigidity, akinesia, tremor, L > R limbs | Decreased uptake in bil. PU, more on R | Decreased uptake in bil. PU, more on R | 0.72 | 0.74 | 0.76 | 0.82 | 0.96 | 1.08 | 0.16 | 0.49 | ||||||||
11 | M | 48 | 5 | II | Rigidity, tremor, L > R limbs, mask face | Decreased uptake in bil. PU, more on R | Decreased uptake in bil. ST | 0.66 | 0.86 | 0.57 | 0.91 | 0.90 | 0.84 | 0.69 | 0.61 | ||||||||
12 | F | 53 | 2 | I | Rigidity, tremor, R limbs | Decreased uptake in bil. PU | Decreased uptake in bil. PU | 0.94 | 0.87 | 0.86 | 0.65 | 1.54 | 1.19 | 1.34 | 0.96 | ||||||||
13 | F | 71 | 6 | III | Rigidity, akinesia, tremor, L > R limbs | Decreased uptake in bil. PU | Decreased uptake in bil. PU, more on L | 0.56 | 0.54 | 0.52 | 0.64 | 1.49 | 1.39 | 1.18 | 0.91 | ||||||||
14 | F | 49 | 3 | I | Rigidity, tremor, L upper limb | Decreased uptake in bil. PU, more on R | Decreased uptake in bil. PU, more on R | 0.78 | 1.00 | 0.76 | 0.91 | 1.61 | 2.15 | 0.90 | 1.25 | ||||||||
15 | F | 74 | 3 | II | Rigidity, akinesia, tremor, L > R limbs | Decreased uptake in bil. PU, more on R | Markedly decreased uptake in bil. ST | 1.16 | 1.40 | 1.11 | 1.29 | 0.77 | 0.53 | 0.69 | 0.39 | ||||||||
16 | M | 56 | 5 | II | Rigidity, akinesia, tremor, L > R limbs | Decreased uptake in bil. PU, more on R | Decreased uptake in bil. PU, more on R | 0.56 | 1.03 | 1.02 | 1.27 | 0.93 | 1.12 | 0.60 | 1.04 | ||||||||
17 | M | 70 | 4 | II | Bradykinesia, tremor, L > R limbs | Decreased uptake in bil. ST | Decreased uptake in bil. PU, more on R | 1.10 | 1.05 | 0.97 | 1.27 | 1.39 | 1.50 | 0.85 | 1.04 | ||||||||
18 | M | 76 | 3 | II | Akinesia, tremor, R > L limbs | Mildly decreased uptake in bil. ST | Decreased uptake in bil. PU | 1.30 | 1.24 | 1.31 | 1.15 | 1.48 | 1.28 | 1.11 | 0.96 | ||||||||
19 | M | 65 | 5 | I | Akinesia, tremor, R limbs | Decreased uptake in L PU | Decreased uptake in bil. PU, more on L | 1.20 | 1.03 | 1.32 | 1.17 | 2.06 | 1.22 | 1.69 | 1.24 | ||||||||
20 | F | 52 | 6 | III | Rigidity, akinesia, tremor, bil. | Decreased uptake in bil. ST | Decreased uptake in bil. ST | 0.54 | 0.52 | 0.48 | 0.47 | 1.10 | 1.02 | 0.57 | 0.69 |
ST = striatum; PU = putamen; CA = caudate; bil. = bilateral.