TABLE 2

Location and Peaks of Significant Adjusted rCBF Decreases or Increases with Advancing Age Before and After PVE Correction

Structure	Coordinate					Z score
Structure		x	y	z		Z score
Before PVE correction
Decrease
L insula	−42	8	−2	5.92
L superior temporal gyrus	−51	3	−9	5.71
R inferior frontal gyrus	40	15	−6	5.37
R superior temporal gyrus	51	5	−9	5.22
R insula	44	8	−2	5.15
R anterior cingulate gyrus	4	36	13	4.99
R parahippocampal gyrus	14	−43	−1	4.81
Increase
L fusiform gyrus	−40	−65	−10	5.84
L inferior occipital gyrus	−34	−84	−6	4.76
R amygdala	26	−12	−9	4.51
R medial frontal gyrus	14	1	59	4.34
After PVE correction
Decrease
L insula	−40	10	−4	6.36
L inferior frontal gyrus	−36	11	−11	6.03
L superior temporal gyrus	−50	3	−9	5.86
R insula	40	13	−6	5.81
R inferior frontal gyrus	46	17	1	5.29
R superior temporal gyrus	46	8	−26	5.29
R middle temporal gyrus	50	9	−17	4.97
R anterior cingulate gyrus	4	34	13	4.96
R parahippocampal gyrus	14	−43	−1	4.9
R superior frontal gyrus	10	56	27	4.59
R medial frontal gyrus	4	55	10	4.56
L anterior cingulate gyrus	−4	33	4	4.52
Increase
R postcentral gyrus	40	−19	49	5.21
L postcentral gyrus	−42	−21	49	5.08
L paracentral lobule	−10	−36	48	5.05
R precuneus	22	−78	39	4.99
L precuneus	−12	−66	38	4.86
R paracentral lobule	10	−35	48	4.79
L middle occipital gyrus	−42	−74	2	4.54