Absorbed Doses to Organs and Tumors of Varying Sizes After Intraperitoneal Injection of 90Y-Trastuzumab
| Organ or tumor | Radius (mm) | Absorbed fraction | Dose (Gy/MBq) |
|---|---|---|---|
| Tumor | 0.1 | 0.017 | 0.10 |
| Tumor | 0.5 | 0.084 | 0.48 |
| Tumor | 1.0 | 0.17 | 0.96 |
| Tumor | 3.0 | 0.45 | 2.6 |
| Tumor | 5.0 | 0.63 | 3.7 |
| Liver | 0.69 | 0.48 | |
| Kidneys | 0.52 | 0.31 | |
| Spleen | 0.34 | 0.56 |
Calculation based on pharmacokinetics and biodistribution of intraperitoneally injected 86Y-trastuzumab.