TABLE 6

Ratios of Absorbed Dose from ⁹⁰Y-Labeled Compounds to Renal Cortex or Renal Medulla, as Determined by Multiregion Kidney Model, to Mean Kidney Dose Assessed in Single-Region Model

Residence time in medulla (%)	Dose ratio for renal cortex: D̄_{cortex-multiregion}/D̄_{kidney-single region} residence time in renal pelvis (%)
Residence time in medulla (%)		0	5	10	15	20	25
0	1.29	1.24	1.18	1.12	1.07	1.01
5	1.24	1.18	1.13	1.07	1.01	0.96
10	1.19	1.13	1.07	1.02	0.96	0.91
15	1.13	1.08	1.02	0.96	0.91	0.85
20	1.08	1.02	0.97	0.91	0.86	0.80
25	1.03	0.97	0.91	0.86	0.80	0.75
30	0.97	0.92	0.86	0.81	0.75	0.69
35	0.92	0.86	0.81	0.75	0.70	0.64
40	0.87	0.81	0.76	0.70	0.64	0.59
45	0.81	0.76	0.70	0.65	0.59	0.53
50	0.76	0.71	0.65	0.59	0.54	0.48

Residence time in medulla (%)	Dose ratio for renal medulla: D̄_{medulla-multiregion}/D̄_{kidney-single region} residence time in renal pelvis (%)
Residence time in medulla (%)		0	5	10	15	20	25
0	0.26	0.27	0.28	0.28	0.29	0.30
5	0.42	0.43	0.44	0.44	0.45	0.46
10	0.58	0.59	0.59	0.60	0.61	0.62
15	0.74	0.75	0.75	0.76	0.77	0.77
20	0.90	0.90	0.91	0.92	0.93	0.93
25	1.05	1.06	1.07	1.08	1.08	1.09
30	1.21	1.22	1.23	1.23	1.24	1.25
35	1.37	1.38	1.39	1.39	1.40	1.41
40	1.53	1.54	1.54	1.55	1.56	1.57
45	1.69	1.69	1.70	1.71	1.72	1.72
50	1.85	1.85	1.86	1.87	1.88	1.88

For both target regions, ratios are given as function of percentage of total kidney residence time within medulla (rows) and renal pelvis (columns), respectively. Difference in total kidney residence time is assigned to renal cortex.