TABLE 2

Characteristics of 17 Patients with Cardiac Sarcoidosis

Patient no.Age (y)SexSymptomInvolved organsACE (IU/L)Lysozyme (μg/mL)ECGEchocardiographySteroid therapy
LV wallLVEF (%)Initial doseOutcome after steroid therapy
129FDyspneaHeart, eye, LN, lung, skin*53.0NAFrequent PVCNormal57ND
235MDyspneaHeart, LN, lung*44.137.4Frequent PVCNormal66ND
348MDyspneaHeart, LN,* lung<1.0NATrifascicular block, VTDiffuse hypokinesis, thinning and akinesis of basal septum41ND
458MSyncopeHeart, LN*10.9NA3rd degree AVB, PMNormal57ND
561FDyspneaHeart, LN,* lung, skin25.8NA3rd degree AVB, PMNormal60ND
662FDyspneaHeart, eye, LN,* lung10.16.53rd degree AVB, PMDiffuse hypokinesis, thinning and akinesis of basal septum37ND
766FDyspneaHeart, LN*NANA3rd degree AVB, PMDiffuse hypokinesis, thinning and akinesis of basal septum34ND
870FPalpitationHeart, LN*NANA3rd degree AVB, PMThinning and akinesis of basal anteroseptal wall50ND
971FSyncopeHeart, LN*13.1NA3rd degree AVB, VTSevere hypokinesis of anterolateral wall61ND
1072FDyspneaHeart, skin*NANAFrequent and short-run PVCDiffuse hypokinesis, thinning and akinesis of basal septum36ND
1153FDyspneaHeart, LN, lung,* skin*31.922.2Poor R in V1,2; Q in V3Normal6440 mg/dNo change
1253FDyspneaHeart, muscle*31.015.02nd degree AVBThinning and akinesis of basal anteroseptal wall5130 mg/dImprovement to 1st degree AVB
1353FSyncopeHeart, eye, LN, lung, skin*29.210.63rd degree AVB, VTDiffuse severe hypokinesis, thinning of basal septum3730 mg/dNo change
1454FPalpitationHeart, muscle*24.513.5Trifascicular block, VTDiffuse hypokinesis, thinning and akinesis of basal septum5030 mg/dDisappearance of VT
1559MDyspneaHeart, muscle,* skin*29.79.73rd degree AVBDiffuse hypokonesis4430 mg/dImprovement to 2nd degree AVB, improvement of LVEF
1665FPalpitationHeart, LN,* lung35.8NANegative T in I and aVL, VTDiffuse hypokinesis, thinning and akinesis of basal septum2630 mg/dNo change
1772FDyspneaHeart, LN,* lung14.09.43rd degree AVB, PMDiffuse severe hypokinesis2530 mg/dNo change
  • * Organ for diagnostic histology.

  • ACE = angiotensin-converting enzyme; ECG = electrocardiography; LVEF = LV ejection fraction; LN = lymph node; NA = not available; PVC = premature ventricular contraction; ND = not done; VT = ventricular tachycardia; AVB = atrioventricular block; PM = permanent pacemaker implanted; aVL = left augmented limb lead.