TABLE 2

Characteristics of Patient Population According to Reincke Clinical Classification

Characteristic	NF	SC-CS	PC-CS	p 1–2	p 1–3	p 2–3
No. of patients	16	9	22
Sex	7 F, 9 M	3 F, 6 M	12 F, 10 M
Age (y)	55.8 ± 12.8	58.5 ± 6.7	53.8 ± 9.8	NS	NS	NS
CT tumor size (cm)	1.9 ± 0.6	2.4 ± 0.6	3.2 ± 1	NS	<0.0001	NS
ACTH at 0800 (ng/L)	24.3 ± 5.8	8.7 ± 1.5	8.5 ± 1.8	<0.0001	<0.0001	NS
Cortisol at 0800 (nmol/L)	389 ± 106	421 ± 72.3	494 ± 197	NS	NS	NS
UFC (nmol/24 h)	202 ± 126.5	223 ± 141.8	439 ± 679.3	NS*	NS*	NS*
DHEA-S at 0800 (μmol/L) (32 patients)	3.9 ± 2.4	1.3 ± 0.7	1.5 ± 0.8	NS^†	NS^†	NS^†
17-OHP (nmol/L) (19 patients)	2.2 ± 1.1	3.8 ± 3.7	1.6 ± 1.4	NS*	NS*	NS*

↵* Not significant, even logarithmic transform.
↵^† Significant, only logarithmic transform.
NF = no functioning adenoma; NS = not significant; p 1–2 = NF vs. SC-CS; p 1–3 = NF vs. PC-CS; p 2–3 = SC-CS vs. PC-CS.
Reincke classification (8).