TABLE 1

Lower Extremity Blood Flow

Subject no.	TD (L/min)					PL (mL/dL/min)
Subject no.		Base	Ad	FR	Base	Ad	FR	Base	Ad	FR
Healthy volunteers
1	0.12	1.6	13.5	2.62	5.14	1.96	0.003	0.063	0.807
2	1.39	6.8	4.9	3.9	9.77	2.51	0.005	0.060	0.453
3	0.37	4.6	12.5	5.89	11.63	1.97	0.003	0.081	0.905
4	0.64	3.7	5.6	2.39	3.69	1.54	0.005	0.073	0.541
5	0.39	3.0	7.7	2.59	8.81	3.4	0.003	0.053	0.578
PAD subjects
6	0.2	1.4	6.8	2.53	9.84	3.89	0.006	0.036	0.212
7	0.2	0.9	4.9	5.43	24.06	4.43	0.004	0.013	0.124
8	0.34	0.75	2.2	4.7	11.28	2.4	0.004	0.022	0.224
9	0.17	0.69	4.1	3.2	9.01	2.82	0.003	0.019	0.206
10	0.29	1.24	4.3	4.5	16.67	3.7	0.003	0.043	0.470

Baseline (Base) and adenosine (Ad)-stimulated measurements of lower extremity blood flow as assessed by 3 different modalities in healthy volunteers and subjects with PAD. FR was calculated as ratio of Ad-to-Base flow.