TABLE 6

Comparison of Several Studies of Contrast Agents and Interference in Radioiodide Thyroid Uptake

ReferenceContrast mediaMeans of administrationTime to return to normal
Rogers and Robbins (21)IodipamideIntravenousAverage 90 d in 4 euthyroid persons
Slingerland (22)Iopanoic acidOral7 d in 1 hyperthyroid person
Newman and Cupp (23)Iodalphionic acidOral30 d in 10 euthyroid persons
Clark and Shipley (24)Iopanoic acidOral60 d in 74 euthyroid persons
Ogden and Sheline (20)Diatrizoate meglumineIntravenous4 d in 19 euthyroid persons
Iopanoic acidOral58 d in 6 euthyroid persons
Jaffiol et al. (25)Ioxaglate meglumineIntravenous30 d in 10 euthyroid persons
This studyDiatrizoate meglumine (282 mg I/kg)Intravenous15 d*
Diatrizoate meglumine (564 mg I/kg)Intravenous15 d*
Iohexol (300 mg I/kg)Intravenous15 d*
Iohexol (600 mg I/kg)Intravenous21 d*
  • * In 5 euthyroid rats.