TABLE 5

Comparison of Relationship Between Dose of Iodide and Percentage Radioiodide Uptake in Thyroid

ReferenceDose of iodideRadioiodide uptake at 24 h* (%)
Hamilton and Soley (11)14 mgNormal, 3.0 (n = 5)
Hyperthyroid, 6.0 (n = 10)
Hypothyroid, 2.5 (n = 1)
Hamilton (12)0.1 μgNormal, 18.5 (n = 3)
Hyperthyroid, 63 (n = 3)
Hypothyroid, 1.5 (n = 4)
Childs et al. (13)0.001 mgHyperthyroid, 70 (n = 7)
1 mgHyperthyroid, 34.3 (n = 7)
10 mgHyperthyroid, 7.6 (n = 7)
100 mgHyperthyroid, 5.5 (n = 1)
380 mgHyperthyroid, 4.0 (n = 1)
Sternthal et al. (14)10 mgEuthyroid, 19.4
After iodide, 12.5 (n = 5)
30 mgEuthyroid, 21.8
After iodide, 1.5 (n = 5)
50 mgEuthyroid, 19.7
After iodide, 1.5 (n = 5)
100 mgEuthyroid, 17.2
After iodide, 0.7 (n = 5)
This study0.76 mg I/kgControl, 9.9 (n = 5)
Treated group, 4.0
1.52 mg I/kgControl, 9.9 (n = 5)
Treated group, 2.8
3.04 mg I/kg§Control, 10.1 (n = 5)
Treated group, 2.7
  • * Percentage administered dose of radioiodide.

  • Value of 1 mg/kg of KI.

  • Value of 2 mg/kg of KI.

  • § Yu (15).