TABLE 4

Results of Student-Newman-Keuls Test of Repeated Measurement Studies for Diatrizoate Meglumine and Iohexol

GroupDay 1*Day 8*Day 15*Day 22*
AControlControlControlControl
Diatrizoate meglumine,  282 mg I/kg Diatrizoate meglumine,  564 mg I/kgDiatrizoate meglumine,  282 mg I/kg Diatrizoate meglumine,  564 mg I/kg
Iohexol, 300 mg I/kgIohexol, 300 mg I/kg
Iohexol, 600 mg I/kg
BDiatrizoate meglumine, 282 mg I/kgDiatrizoate meglumine, 282 mg I/kgIohexol, 600 mg I/kg
Diatrizoate meglumine, 564 mg I/kg
CDiatrizoate meglumine, 564 mg I/kgIohexol, 300 mg I/kg Iohexol, 600 mg I/kg
DIohexol, 300 mg I/kg
Iohexol, 600 mg I/kg
  • * Radioiodide administered 24 h before determination of thyroid uptake.

  • Time after termination of administration of interfering agent.

  • Student-Newman-Keuls test controls type I experiment-wise error rate (α = 0.05) under complete null hypothesis but not under partial null hypotheses.