TABLE 1

Effect of KI and PTU on Radioiodide Thyroid Uptake

GroupDay 1*Day 8*Day 15*Day 22*
Control9.9 ± 0.712.0 ± 1.210.9 ± 0.510.8 ± 1.3
KI
 1 mg/kg4.0 ± 0.711.2 ± 1.815.2 ± 0.69.8 ± 1.0
 2 mg/kg2.8 ± 0.411.6 ± 1.114.7 ± 0.59.9 ± 1.0
PTU
 3.5 mg/kg2.9 ± 0.87.4 ± 1.211.5 ± 0.511.2 ± 1.6
 7 mg/kg2.8 ± 0.68.3 ± 1.510.9 ± 0.59.9 ± 1.1
  • * Radioiodide administered 24 h before determination of thyroid uptake.

  • Time after termination of administration of interfering agent.

  • Data are expressed as percentage radioiodide thyroid uptake (mean ± SD; n = 5 rats per group).