q
| Cumulated activity per unit mass of tissue | MBq s g−1 |
z̄
| Average specific energy to the nucleus of a target cell | Gy |
T
z
| Survival probability to a target cell for cell sensitivity z0 | Unitless |
ẑ
| Normalized absorbed dose: absorbed dose per unit cumulated activity concentration | Gy g MBq−1 s−1 |
n̂
| Normalized average number of hits: average number of hits per unit cumulated activity concentration | hits g MBq−1 s−1 |
T̂
z0
| Normalized survival probability: probability of survival per unit cumulated activity concentration for cell sensitivity z0 | Unitless |
T̂
z=0
| Normalized probability of zero hits: probability of zero hits per unit cumulated activity concentration | Unitless |
pdf(ẑ) | Probability density function for the normalized absorbed dose for all target cells | MBq s Gy−1 g−1 |
pdf(T̂z0) | Probability density function for the normalized survival probability for all target cells for a given cell sensitivity z0 | Unitless |
〈ẑ〉 | Average normalized absorbed dose among all target cells | Gy g MBq−1 s−1 |
〈T̂z0〉 | Average normalized survival probability among all target cells | Unitless |
F
<
| Fraction of tumor cells receiving a normalized absorbed dose lower than 〈ẑ〉h | Unitless |
F
>
| Fraction of tumor cells receiving a normalized absorbed dose higher than 〈ẑ〉h | Unitless |
F
0
| Fraction of tumor cells receiving a zero normalized absorbed dose—i.e., ẑ = 0 | Unitless |
pti
| Probability of tumor incidence among all analyzed histological samples | Unitless |
SF(q) | Survival fraction of tumor cells as a function of cumulated activity concentration q | Unitless |
〈ẑ〉uNT | Normal tissue CPE ratio, 〈ẑ〉NT/〈ẑ〉u | Unitless |
〈ẑ〉uTT | Tumor tissue CPE ratio, 〈ẑ〉TT/〈ẑ〉u | Unitless |
τlung | Residence time in lung tissue | s |