Scheme of Study Protocol
| Experiment no. | Intervention | Experimental condition | Measurement |
|---|---|---|---|
| 1 | — | Control | MS + 3H-label, IDC |
| 2 | — | Control | MS + 3H-label |
| 3 | EHNA | Inhibition of adenosine deamination | MS + 3H-label |
| 4 | EHNA | Inhibition of adenosine deamination | MS + 3H-label, IDC |
| 5 | Coronary occlusion + alprostadil | Ischemia/hyperemia | MS + 3H-label |
| 6 | Coronary occlusion + alprostadil | Ischemia/hyperemia | MS + 3H-label |
| 7 | Coronary occlusion + alprostadil | Ischemia/hyperemia | MS + 3H-label + 14C-label |
MS = microsphere deposition density; 3H-label = 3H-label deposition density; IDC = indicator dilution curve; 14C-label = 14C-label deposition density.