TABLE 2

Advantage of Auger Electron Emitters in Cytotoxicity of Raji Cells Relative to 131I

RadionuclideRatio of specific toxicity*Ratio of nonspecific toxicity
L2431F5
131I1.001.001.00
125I0.3310.2260.096
111In0.1830.1390.248
67Ga0.4740.3160.292
  • * (Decays per cell of 131I required for 2.5 logarithms of cell kill)/(decays per cell of other radionuclide required for same level of kill).

  • (Decays per well of 131I required for 2 logarithms of cell kill)/(decays per well of other radionuclide required for same level of kill).