Therapy Response Scores with Respect to Different Sites of Application, Different Cumulative Activities of 186Re-Colloid, and Mean Biologic Half-Life Values
| Patient no. | Application site | Cumulative activity (MBq) | Biologic t1/2 (h) | Score | Evaluation (mo after last RTSO) | ||
|---|---|---|---|---|---|---|---|
| Subj. | Obj.* (methods) | ||||||
| 1 | TYR | 90 | 37.8 ± 13.3 | +1 | +1 (A, E, CT) | 8 | |
| TYL | 80 | 39.0 ± 9.9 | +1 | +1 (A, E, CT) | 8 | ||
| FSR | 40 | 29.0 ± 15.7 | +2 | +2 (A, E, CT) | 14 | ||
| FSL | 40 | 29.0 ± 15.7 | +2 | +2 (A, E, CT) | 14 | ||
| MSR | 55 | 19.7 ± 6.0 | +2 | 0† (A, E, CT) | 20 | ||
| MSL | 55 | 19.7 ± 6.0 | +2 | +2 (A, E, CT) | 20 | ||
| 2 | FSR | 20 | 23 | +1 | 0 (E, CT, H) | 6 | |
| FSL | 20 | 23 | +1 | 0 (E, CT) | 6 | ||
| MSR | 20 | 26 | +1 | 0 (E, CT, H) | 6 | ||
| MSL | 20 | 26 | +1 | 0 (E, CT) | 6 | ||
| 3 | TYR | 50 | 66.3 ± 14.2 | +2 | 0 (A, E, CT) | 7 | |
| TYL | 50 | 54.7 ± 3.0 | +2 | +2 (A, E, CT) | 7 | ||
| MSR | 20 | 43 | +1 | 0 (A, E, CT) | 7 | ||
| MSL | 20 | 43 | +1 | 0 (A, E, CT) | 7 | ||
| 4 | TYR | 20 | 44 | +2 | +1 (A, E, CT) | 6 | |
| 5 | TYR | 40 | 51.0 ± 4.2 | +1 | —‡ | 14 | |
| TYL | 40 | 54.0 ± 8.5 | +1 | —‡ | 14 | ||
| 6 | TYR | 20 | 39 | +2 | +2 (A, E, CT) | 20 | |
| Mean ± SD | +1.44 ± 0.5 | +0.81 ± 0.9 | |||||
↵* Estimation of objective score: A = audiometry; CT = CT scan; E = endoscopy with rigid and flexible endoscope and microscope; H = histologic findings.
↵† Obliteration of right maxillary sinus after surgery.
↵‡ Evaluation only by telephone call.
Subj. = subjective; Obj. = objective; TYR or TYL = right or left tympanic cavity; FSR or FSL = right or left frontal sinus; MSR or MSL = right or left maxillary sinus.
Only 1 radionuclide application was performed in patients 2, 4, and 6 as well as in maxillary sinuses of patient 3.