Pharmacokinetic Parameters vs. Hematologic Nadir Grade
| Nadir grade | Whole blood effective t1/2 (h) | Whole blood AUC (h) | ||
|---|---|---|---|---|
| ANC | ||||
| 0–2 | 0.27 | 0.25 | ||
| 3 | 0.29 | 0.24 | ||
| 4 | 0.27 | 0.24 | ||
| P = 0.050 | P = 0.898 | |||
| Platelet count | ||||
| 0–2 | 0.27 | 0.26 | ||
| 3 | 0.27 | 0.24 | ||
| 4 | 0.27 | 0.20 | ||
| P = 0.547 | P = 0.594 | |||