TABLE 2

Organ Radiation Absorbed Dose (Gy) from ⁹⁰Y

Organ	7.4 MBq/kg (0.2 mCi/kg)					11 MBq/kg (0.3 mCi/kg)					15 MBq/kg (0.4 mCi/kg)
Organ		n	Median	Range	n	Median	Range	n	Median	Range	n	Median	Range
Spleen	2	1.64	0.23–3.05	46	5.80	1.65–17.11	118	8.17	0.76–24.48	166	7.42	0.23–24.48
Liver	4	4.04	2.20–6.23	46	3.48	0.64–15.81	129	4.67	1.22–18.56	179	4.50	0.64–18.56
Lungs	4	1.15	0.72–1.76	46	1.73	0.41–2.95	129	2.25	0.94–5.27	179	2.11	0.41–5.27
Red marrow (blood-derived)	4	0.19	0.13–0.38	46	0.47	0.06–0.95	129	0.69	0.18–2.21	179	0.62	0.06–2.21
Kidneys*	4	0.17	0.09–0.29	46	0.26	0.00–0.65	129	0.23	0.00–0.76	179	0.23	0.00–0.76
Bone surfaces^†	4	0.18	0.12–0.35	46	0.44	0.06–0.72	129	0.59	0.20–1.57	179	0.54	0.06–1.57
Urinary bladder wall^‡	4	0.52	0.33–0.68	46	0.87	0.41–2.53	129	0.89	0.38–2.70	179	0.87	0.33–2.70
Total body	4	0.29	0.24–0.36	46	0.46	0.28–0.67	129	0.60	0.23–0.80	179	0.57	0.23–0.80
Other organs^§	4	0.17	0.09–0.29	46	0.33	0.06–0.55	129	0.44	0.12–0.61	179	0.40	0.06–0.61

↵* Actual minimal kidney dose was 0.03 cGy; here it is rounded to 0.0 Gy.
↵^† Dose to bone surfaces includes contributions from both red marrow and whole-body remainder residence times.
↵^‡ Absorbed dose to urinary bladder wall from ⁹⁰Y activity in urine was estimated using difference in total-body radioactivity observed at time 0 and that observed at later time points (corrected for decay) and assuming that voiding occurs every 4.8 h.
↵^§ Includes adrenals, brain, breasts, gallbladder wall, heart wall, lower large intestine wall, muscles, pancreas, skin, small intestine, stomach, thymus, thyroid, upper large intestine wall, and ovaries and uterus (female patients) or testes (male patients).