Comparison of 18F-FDG PET (Early Imaging, Delayed Imaging, and RI) and 201Tl SPECT Results for Diagnosis of Malignancy
| Thoracic lesion | 18F-FDG PET | 201Tl SPECT RI (%) | ||||
|---|---|---|---|---|---|---|
| Early imaging (%) | Delayed imaging (%) | RI (%) | ||||
| Low-grade malignancy | 2/4 (50.0) | 2/4 (50.0) | 4/4 (100.0) | 3/4 (75.0) | ||
| Well-diff. carcinoma | 8/19 (42.1) | 9/19 (47.4) | 18/19 (94.7) | 6/19 (31.6) | ||
| Moderately diff. carcinoma | 8/8 (100.0) | 8/8 (100.0) | 8/8 (100.0) | 7/8 (87.5) | ||
| Poorly diff. carcinoma | 13/13 (100.0) | 13/13 (100.0) | 13/13 (100.0) | 10/13 (76.9) | ||
| Undiff. carcinoma | 6/6 (100.0) | 6/6 (100.0) | 6/6 (100.0) | 5/6 (83.3) | ||
| Benign disease (including granulomatous disease) | 15/30 (50.0) | 17/30 (56.7) | 20/30 (66.7) | 24/30 (80.0) | ||
| Sensitivity (%) | 74.00 | 76.00 | 98.00 | 63.30 |
| Specificity (%) | 50.00 | 56.70 | 66.70 | 80.00 |
| Accuracy (%) | 65.0* | 68.8* | 86.30 | 68.8* |
↵* P < 0.01 vs. RI of 18F-FDG PET.
Diff. = differentiated; Undiff. = undifferentiated.
Accuracy of 18F-FDG PET RI was significantly higher than that of other modalities.