TABLE 2

Plasma Substrates, Glycogen, and Hexokinase Activity After Final Episode of Ischemia

GroupPlasma substrateGlycogenHexokinase activity
Glucose (μmol/mL)Lactate (μmol/mL)Fatty acids (μmol/L)Circumflex (μmol/g)Remote (μmol/g)Circumflex (IU/g)Remote (IU/g)
14.5 ± 0.051.0 ± 0.2583 ± 2923 ± 220 ± 20.35 ± 0.030.35 ± 0.04
25.4 ± 0.131.0 ± 0.1603 ± 5521 ± 324 ± 40.26 ± 0.030.28 ± 0.05
  • Insulin levels in all animals were <2.0 μU/mL. Arterial plasma substrates were sampled midway through 18F-FDG PET scan, and glycogen and hexokinase activities were determined from biopsy samples harvested immediately after PET scan. Data are expressed as mean ± SEM.