TABLE 1

Comparison of Correlation Coefficients Between Unadjusted and FLT3-L–Adjusted Toxicity Predictors

Method	Correlation coefficients (r)
		Red marrow dose (cGy)			Total body dose (cGy)	Activity (GBq)	Activity/body weight (GBq/kg)
		CF = 0.3	CF = 0.19/(1 − hct)		Total body dose (cGy)	Activity (GBq)	Activity/body weight (GBq/kg)
MIRDOSE3
All males
Equation 3
PTG	0.28 (0.70)	0.25 (0.70)	0.23 (0.68)	0.05 (0.61)	0.28 (0.72)
PPD	0.15 (0.48)	0.10 (0.47)	0.06 (0.46)	0.15 (0.51)	0.33 (0.59)
PN	0.22 (0.76)	0.20 (0.76)	0.16 (0.75)	0.03 (0.60)	0.18 (0.75)
1/PN	0.20 (0.86)	0.19 (0.85)	0.17 (0.86)	0.21 (0.53)	0.04 (0.79)
Equation 2
PTG	0.31 (0.68)	0.28 (0.68)
PPD	0.15 (0.46)	0.12 (0.46)
PN	0.27 (0.75)	0.24 (0.74)
1/PN	0.21 (0.84)	0.17 (0.82)
Males and females
Equation 3
PTG	0.31 (0.68)	0.27 (0.68)
PPD	0.15 (0.46)	0.11 (0.45)
PN	0.27 (0.74)	0.24 (0.74)
1/PN	0.20 (0.86)	0.18 (0.85)
MIRD 11
Equation 3
PTG	0.31 (0.67)	0.26 (0.67)
PPD	0.17 (0.46)	0.12 (0.46)
PN	0.28 (0.73)	0.23 (0.71)
1/PN	0.20 (0.85)	0.16 (0.82)

All correlation coefficients were obtained using either MIRDOSE3 or MIRD 11 parameters, either Equation 2 or Equation 3, and CF equal to 0.3 or 0.19/(1 − hematocrit [hct]), as indicated. Values are correlation coefficients obtained using unadjusted toxicity predictors (values in parentheses are FLT3-L–adjusted correlation coefficients).