TABLE 1

Ratios Derived from PET Data Comparing Target-to-Background Levels of ¹²⁴I Activity

Ratio	Minibody (n = 8)			Diabody (n = 4)
Ratio		4 h	18 h	4 h	18 h
LS174T to C6	3.46 ± 0.72	10.85 ± 2.03*	3.99 ± 0.98	—^†
LS174T to background	0.78 ± 0.10	3.48 ± 0.48*	1.83 ± 0.40	6.11 ± 1.49^‡
LS174T to soft tissue	3.05 ± 0.72	11.03 ± 2.35*	3.95 ± 1.27	10.93 ± 2.21^‡

↵* Significantly different from 4 h (minibody group; P < 0.05, paired t test).
↵^† Could not be calculated, as C6 tumor was not distinguishable.
↵^‡ Significantly different from 4 h (diabody group; P < 0.05, paired t test).
Data are mean ± SEM. Background is abdominal region.