TABLE 2

Comparisons Between TK1 Activity, S-Phase Fraction, and Tracer Uptake

TracerTK1 activityS-phase fraction
r2Pr2P
TdR
 All 6 cell lines0.56<0.00010.66<0.0001
 A549, HT29, WiDr, EMT60.90<0.00010.920.001
 RIF1, KHTn0.360.040.640.001
FLT
 All 6 cell lines0.80<0.00010.63<0.0001
 A549, HT29, WiDr, EMT60.90<0.00010.94<0.0001
 RIF1, KHTn0.230.090.480.008
FMAU
 All 6 cell lines−0.030.19−0.020.48
 A549, HT29, WiDr, EMT60.200.020.250.009
 RIF1, KHTn−0.010.370.010.31
  • Data are normalized to plateau values.