Tumor Dosimetry
| Patient | Tumor location | L × W | Mass* (g) | Tumor dose | % change† | Tumor/organ absorbed-dose ratio | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| mGy/MBq | cGy | RM | WB | Lv | Lu | Kid | Spl | |||||||||||
| 1-3 | R paratracheal | 3.0 × 2.2 | 9.2 | 60.3 | 2,927 | −82 | ND | 85.9 | 9.5 | 22.3 | ND | 3.3 | ||||||
| 1-4 | Axillary | 5.5 × 5.0 | 82.4 | 7.2 | 374 | Prog | 3.4 | 8.9 | 1.7 | 4.2 | 2.8 | ND | ||||||
| 1-7 | L medial supraclavical | 1.2 × 1.0 | 0.7 | 7.1 | 474 | −100 | 3.9 | 9.0 | ND | 3.3 | 1.8 | 1.0 | ||||||
| Internal mammary | 1.7 × 2.2 | 3.9 | 83.5 | 5,587 | −4.0 | 46.1 | 106 | 12.7 | 39.1 | 21.4 | 12.3 | |||||||
| 2-8 | Iliac wing | 13.0 × 8.0 | 606.1 | 1.7 | 50 | −60 | 1.1 | 2.1 | 0.5 | 0.6 | 0.5 | 0.3 | ||||||
| 1-11 | R anterior supraclavicular | 2.0 × 1.3 | 2.4 | 10.2 | 883 | −73 | 7.7 | 12.6 | 3.9 | 6.4 | 4.8 | 1.3 | ||||||
| Lower axilla | 2.0 × 0.9 | 1.6 | 23.0 | 1,981 | −99 | 17.3 | 28.3 | 8.7 | 14.4 | 10.8 | 3.0 | |||||||
| 1-12 | L inguinal | 3.8 × 3.2 | 22.4 | 4.2 | 648 | −77 | 2.2 | 6.7 | 1.6 | 2.3 | 2.3 | 1.4 | ||||||
| 2-10 | External iliac | ND | 2.6 | 11.3 | 878 | Prog | 8.7 | 19.9 | 3.1 | 6.0 | 4.8 | 2.0 | ||||||
| 1-13 | Subclavicular | 3.2 × 2.3 | 10.9 | 6.9 | 899 | ND | 3.1 | 11.5 | 2.0 | 3.6 | 2.9 | 1.1 | ||||||
| 2-11 | Common femoral | 3.0 × 2.0 | 10.9 | 1.8 | 147 | −64 | 0.9 | 2.9 | 0.6 | 0.7 | 0.5 | 0.3 | ||||||
| Inguinal | 2.8 × 2.9 | 8.2 | 1.2 | 94 | −86 | 0.6 | 1.9 | 0.4 | 0.5 | 0.3 | 0.2 | |||||||
| 2-12 | L lower neck | 8.0 × 6.0 | 179.6 | 1.0 | 71 | Prog | 1.7 | 1.6 | 0.3 | 1.0 | 0.3 | ND | ||||||
| R inguinal | 2.0 × 2.0 | 4.2 | 12.5 | 1,053 | Prog | 25.7 | 24.3 | 3.9 | 15.4 | 5.4 | ND | |||||||
↵* Tumor mass was calculated by assuming a radius equal to average of 2 diameters ÷ 2—that is, volume = 4/3π ([L + W]/2 ÷ 2)3.
↵† Maximum % change in size of lesion (i.e., it does not represent overall response).
L × W = length × width; RM = red marrow; WB = whole-body; Lv = liver; Lu = lungs; Kid = kidneys; Spl = spleen; ND = not determined because of overlying disease (patient 1-3), overlying heart and liver (patient 1-4), or multiple lesions in liver (patient 1-7) and enlarged and lymphomatous spleen (i.e., neither was considered normal) in patient 2-12. Patient 2-10 baseline CT was not measured; Prog = disease progressed, no baseline or follow-up measurements made.