TABLE 1

Changes in CBF and V0 in ACZ Test and Other Parametric Values (Mean ± SD)

ParameterPatients with CVD (n = 22)
IpsilateralContralateral
CBF (mL/min/100 g)
 Baseline36.5 ± 8.1*40.8 ± 6.8
 ACZ41.5 ± 11.2*54.7 ± 9.5
 Change (%)13.6 ± 20.2*35.1 ± 17.6
V0 (mL/100 g)
 Baseline1.73 ± 0.50*2.11 ± 0.51
 ACZ2.23 ± 0.61*2.94 ± 0.73
 Change (%)31.8 ± 26.1§42.6 ± 30.7
CMRo2 (mL/min/100 g)2.71 ± 0.44§2.99 ± 0.33
OEF (%)50.2 ± 7.4§47.7 ± 6.2
CBV (mL/100 g)4.21 ± 0.50§3.90 ± 0.49
  • * P < 0.001

  • § P < 0.005 comparing between bilateral hemispheres (repeated-measures ANOVA and paired t test).

  • P < 0.005

  • P < 0.001 comparing before and after ACZ administration (repeated-measures ANOVA and paired t test).

  • Values are given for regions of bilateral MCAs.