TABLE 1

VDs and BPs in Human Brain

ModelCerebellumThalamusCaudatePutamen
VD 2-compartment2.42 ± 0.352.96 ± 0.287.19 ± 2.458.18 ± 1.89
BP 2-compartment*—0.23 ± 0.081.92 ± 0.592.36 ± 0.33
VD 3-compartment2.34 ± 0.392.77 ± 0.307.20 ± 2.458.18 ± 1.85
BP 3-compartment0.13 ± 0.140.20 ± 0.180.65 ± 0.751.03 ± 0.74
VD Logan invasive2.53 ± 0.382.78 ± 0.337.21 ± 2.438.25 ± 1.92
BP Logan invasive*—0.13 ± 0.131.81 ± 0.572.25 ± 0.36
BP Logan noninvasive00.13 ± 0.141.77 ± 0.522.20 ± 0.30
BP reference tissue—0.17 ± 0.081.82 ± 0.582.28 ± 0.35
BP equilibrium—0.20 ± 0.131.70 ± 0.312.19 ± 0.42

  • ↵* Indirect estimate, determined from respective VD.

  • Logan invasive model = Logan plot with arterial blood sampling; Logan noninvasive method = Logan plot with reference region.