Biodistribution of 125I-ITdU in Normal Mice (n = 3)
| Organ | 1 h | 1.5 h | 2 h | 8 h | 18 h |
|---|---|---|---|---|---|
| Blood | 2.5 ± 0.3 | 2.6 ± 0.6 | 1.6 ± 0.7 | 0.7 ± 0.2 | 0.1 ± 0.0 |
| Spleen | 1.1 ± 0.1 | 1.7 ± 0.3 | 1.1 ± 0.3 | 0.5 ± 0.1 | 0.3 ± 0.0 |
| Intestine | 1.9 ± 0.1 | 1.9 ± 0.5 | 1.7 ± 0.4 | 1.7 ± 0.5 | 0.9 ± 0.1 |
| Thymus | 1.8 ± 0.1 | 1.8 ± 0.4 | 1.4 ± 0.7 | 2.2 ± 1.3 | 1.1 ± 0.4 |
| Femur | 1.0 ± 0.1 | 1.0 ± 0.2 | 0.9 ± 0.2 | 0.7 ± 0.1 | 0.2 ± 0.0 |
| Thyroid | 23.0 ± 6.4 | 23.1 ± 12.5 | 16.3 ± 9.7 | 16.0 ± 2.7 | 1.1 ± 0.3 |
| Lung | 1.4 ± 0.1 | 1.5 ± 0.3 | 1.1 ± 0.5 | 0.5 ± 0.1 | 0.1 ± 0.0 |
| Heart | 1.0 ± 0.1 | 1.3 ± 0.3 | 0.8 ± 0.4 | 0.2 ± 0.1 | 0.0 ± 0.0 |
| Muscle | 0.5 ± 0.2 | 0.7 ± 0.2 | 0.5 ± 0.2 | 0.1 ± 0.1 | 0.0 ± 0.0 |
| Liver | 1.1 ± 0.2 | 1.5 ± 0.4 | 0.9 ± 0.5 | 0.2 ± 0.1 | 0.0 ± 0.0 |
| Brain | 0.1 ± 0.0 | 0.2 ± 0.1 | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| Kidney | 9.5 ± 3.5 | 5.8 ± 4.1 | 1.9 ± 1.7 | 0.5 ± 0.1 | 0.1 ± 0.0 |
Data are expressed as percentage injected dose per gram (mean ± SD).