Biodistribution of 125I-IUdR in Normal Mice (n = 3)
Organ | 1 h | 1.5 h | 2 h | 8 h | 18 h |
---|---|---|---|---|---|
Blood | 7.6 ± 0.8 | 5.4 ± 1.2 | 5.3 ± 0.5 | 1.1 ± 0.1 | 0.8 ± 1.1 |
Spleen | 4.7 ± 0.6 | 4.6 ± 1.2 | 4.7 ± 2.2 | 3.1 ± 1.5 | 1.7 ± 0.9 |
Intestine | 5.0 ± 0.2 | 3.3 ± 0.7 | 4.5 ± 0.5 | 2.4 ± 0.2 | 1.4 ± 0.4 |
Thymus | 6.6 ± 1.1 | 4.4 ± 1.6 | 4.3 ± 1.0 | 1.8 ± 0.3 | 1.8 ± 1.5 |
Femur | 4.5 ± 0.5 | 3.6 ± 0.8 | 3.7 ± 0.5 | 1.6 ± 0.1 | 1.1 ± 0.4 |
Thyroid | 113.0 ± 30.8 | 80.7 ± 51.9 | 112.1 ± 22.3 | 32.9 ± 13.5 | 9.7 ± 8.0 |
Lung | 5.1 ± 0.4 | 3.6 ± 0.8 | 3.6 ± 0.3 | 0.9 ± 0.4 | 0.6 ± 0.7 |
Heart | 2.8 ± 0.5 | 2.1 ± 0.5 | 1.9 ± 0.1 | 0.4 ± 0.0 | 0.3 ± 0.3 |
Muscle | 1.4 ± 0.2 | 1.5 ± 0.3 | 1.4 ± 0.5 | 0.3 ± 0.1 | 0.1 ± 0.2 |
Liver | 2.7 ± 0.4 | 2.1 ± 0.5 | 1.9 ± 0.2 | 0.4 ± 0.1 | 0.3 ± 0.3 |
Brain | 0.3 ± 0.0 | 0.2 ± 0.1 | 0.2 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
Kidney | 5.9 ± 0.4 | 4.8 ± 1.5 | 3.4 ± 0.3 | 0.7 ± 0.1 | 0.6 ± 0.8 |
Data are expressed as percentage injected dose per gram (mean ± SD).