TABLE 1

Relative Phosphorylation of Iodonucleosides by Nucleoside Kinases

Nucleosidepmol phosphorylated*Relative potency
IUdR1,620.8 ± 123.41.00
ITdU802.4 ± 67.90.50
ITAU13.3 ± 0.6<0.01

  • ↵* pmol phosphorylated = pmol/mg protein/h.