TABLE 2

Clinical Response Indicators

Patient no.	Tumor type	Weight (kg)			Health state score			Karnofsky score			Fatigue	Abdominal pain	Diarrhea	N/V	Flushing	Overall clinical response
Patient no.	Tumor type			Before	After	Before	After	Before	After		Fatigue	Abdominal pain	Diarrhea	N/V	Flushing	Overall clinical response
1	Carcinoid	56.3	54.6	80	75	90	90	Unchanged	Improved	N/A	N/A	N/A	−1
2	Islet cell	56.5	62.6	80	90	80	90	Improved	N/A	N/A	Improved	N/A	4
3	Carcinoid	70	78.1	80	80	90	100	Improved	N/A	N/A	N/A	N/A	3
4	Carcinoid	62	62.9	60	85	80	90	Improved	Improved	N/A	Improved	Unchanged	3
5	Islet cell	64.5	57	65	50	80	70	Worsened	Unchanged	N/A	Unchanged	N/A	−4
6	Glucagonoma	88	93.5	80	73	90	90	Improved	Improved	Unchanged	Unchanged	N/A	2
7	Neuroendo/ unknown origin	87.8	97	62	90	80	100	Improved	N/A	Improved	Improved	N/A	4
8	Carcinoid	78	79	70	75	70	80	Improved	Unchanged	N/A	Unchanged	N/A	2
9	Carcinoid	117	113	80	75	90	90	Unchanged	Improved	Improved	N/A	N/A	1
10	Carcinoid	66	69.4	40	90	90	90	Improved	Improved	Unchanged	N/A	Improved	3
11	Carcinoid	104	107	80	85	90	100	Improved	N/A	N/A	N/A	Improved	2
12	Carcinoid	64	64	82	70	90	90	Unchanged	Improved	Unchanged	N/A	Improved	0
13	Carcinoid	73	74.3	70	80	90	90	Unchanged	Improved	Improved	N/A	Improved	2
14	Carcinoid	58	54	70	80	90	90	Improved	Improved	Unchanged	Improved	N/A	1
15	Carcinoid	84	84	75	80	90	95	Improved	N/A	N/A	N/A	Improved	1
16	Carcinoid	73	73	50	70	70	80	Improved	N/A	N/A	N/A	Improved	3
17	Carcinoid	115	120	50	40	80	70	Unchanged	N/A	Worsened	N/A	Unchanged	−3
18	Carcinoid	66	68	70	98	90	90	Unchanged	N/A	N/A	N/A	Improved	2
19	Carcinoid	66	62	60	75	80	90	Unchanged	N/A	Improved	N/A		2
20	Carcinoid	106	105	45	60	80	80	N/A	N/A	Improved	N/A	Improved	2
21	Carcinoid	59	59	75	76	80	90	Improved	Improved	Improved	N/A	Improved	2