TABLE 1

Scoring System for Clinical Response Score

Favorable response criteria*Unfavorable response criteria
•Improvement of at least 1 major symptom without worsening of others•Worsening of any symptom
•Improvement of Karnofsky score by 10 points or more•Worsening of Karnofsky score by 10 points or more
•Weight gain of 5% or more•Weight loss of more than 5%
•Improvement of health state score by at least 10 points•Worsening of health state score by at least 10 points
  • * Assigned +1 for each one present and 0 if absent.

  • Assigned −1 for each one present and 0 if absent.