Patient no. | Age (y) | Histology | Ann Arbor stage | Tumor size | After 1 cycle | After completion | Outcome | PFS (mo) |
---|---|---|---|---|---|---|---|---|
1 | >60 | DLCL | IIIB | Bulky | + | − (FN) | Relapse | 18 |
2 | >60 | DLCL | IIA | Nonbulky | + | − (FN) | Relapse | 10 |
3 | <60 | DLCL | IIB | Bulky | + | − (FN) | Relapse | 6 |
4 | >60 | FLC | IIIA | Bulky | − | − | Remission | 24 |
5 | <60 | HD | IIB | Bulky | + (FP) | + (FP) | Remission | 18 |
6 | <60 | HD | IIA | Bulky | − | − | Remission | 20 |
7 | >60 | DLCL | IIA | Bulky | − | − | Remission | 19 |
8 | >60 | FLC | IV | Nonbulky | − | − | Remission | 20 |
9 | DLCL | + | − (FN) | Relapse | 7 | |||
10 | DLCL | + | + | NFOD | 0 | |||
11 | HD | − (FN) | + | Relapse | 4 | |||
12 | LL | + | + | NFOD | 0 | |||
13 | HD | + | − (FN) | Relapse | 5 | |||
14 | DLCL | + | + | NFOD | 0 | |||
15 | DLCL | − (FN) | − (FN) | Relapse | 6 | |||
16 | DLCL | − | − | Remission | 18 | |||
17 | HD | + | + | NFOD | 0 | |||
18 | DLCL | − | − | Remission | 18 |
After 1 cycle = 18F-FDG PET after first cycle of chemotherapy; After completion = 18F-FDG PET after completion of chemotherapy; DLCL = diffuse large cell lymphoma; FN = false-negative; FLC = follicular large cell lymphoma; FP = false-positive; NFOD = never free of disease; LL = lymphoblastic lymphoma.
Patients 1–8 had poor prognostic features at initial staging; patients 9–18 were included in study at relapse.