TABLE 2

Summary of LS174T Tumor Growth in Athymic Mice After Combination 131I-B72.3 RIT with 1 Dose of AP

Parameter0.1 mg AP control9.25 MBq 131I-B72.3 plus
0 mg AP control0.1 mg AP
Initial tumor size* (mm3)76 ± 15112 ± 2299 ± 20.0
Tumor size on day 15* (mm3)1,941 ± 315447 ± 102245 ± 74.0
Tumor Tq* (d)7.1 ± 0.414.2 ± 3.326.0 ± 3.6
Specific growth delay§012.7
  • * Mean ± SE.

  • P < 0.001 at 0.05 significance level for both AP-treated groups.

  • 0.01 > P > 0.02 at 0.05 significance level between 2 AP-treated groups.

  • § Specific growth delay = (Tq treated − Tq control)/Tq control (11).