TABLE 2

Hepatic Bile Transit Within Gallbladder Lumen in Control Subject and in Patient with CAC

Time after 99mTc-HIDA (min)1234567891011121314151617181920
No. of pixels
 Control subject 2090000000005243849578179106120133
 CAC patient 138000000000001124183536445461
Time after 99mTc-HIDA* (min)2122232425262728293031323334353637383940
No. of pixels*
 Control subject 209135154152167184186198204199221199213216233224238220225246248
 CAC patient 138788180101107105109115126130128137138155155151155162154168
Time after 99mTc-HIDA* (min)4142434445464748495051525354555657585960
No. of pixels*
 Control subject 209240255255251251253259252252258242273233256269255257258237267
 CAC patient 138166172174171182179190174180182189182199174184179194179190180
  • * Data are continuations of subsequent set of data.

  • Calculations for control subject 209:

    Hepatic bile area = Number of pixels × pixel area.

    Initial hepatic bile area = 5 × 10.95 = 55 mm2.

    Maximum hepatic bile area = 233 × 10.95 = 2,551 mm2.

    Net hepatic bile transit area = 2,551 − 55 = 2,496 mm2.

    Hepatic bile transit time = 34 − 11 = 23 min.

    Hepatic bile transit rate = 2,496/23 = 109 mm2/min.

    Adjusted transit rate = 108 × 1,000/2,551 = 42 mm2/min/1,000 mm2.

  • Note that minimum number of hepatic bile pixels in frames between 51 and 60 min was 233 at 53 min. However, this low number was seen first at 34 min, indicating that gallbladder complete filling with radiolabeled hepatic bile occurred earlier at this time interval.