Time after 99mTc-HIDA (min) | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 |
No. of pixels | ||||||||||||||||||||
Control subject 209 | — | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 24 | 38 | 49 | 57 | 81 | 79 | 106 | 120 | 133 |
CAC patient 138 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11 | 24 | 18 | 35 | 36 | 44 | 54 | 61 | |
Time after 99mTc-HIDA* (min) | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 |
No. of pixels* | ||||||||||||||||||||
Control subject 209 | 135 | 154 | 152 | 167 | 184 | 186 | 198 | 204 | 199 | 221 | 199 | 213 | 216 | 233 | 224 | 238 | 220 | 225 | 246 | 248 |
CAC patient 138 | 78 | 81 | 80 | 101 | 107 | 105 | 109 | 115 | 126 | 130 | 128 | 137 | 138 | 155 | 155 | 151 | 155 | 162 | 154 | 168 |
Time after 99mTc-HIDA* (min) | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 |
No. of pixels* | ||||||||||||||||||||
Control subject 209 | 240 | 255 | 255 | 251 | 251 | 253 | 259 | 252 | 252 | 258 | 242 | 273 | 233 | 256 | 269 | 255 | 257 | 258 | 237 | 267 |
CAC patient 138 | 166 | 172 | 174 | 171 | 182 | 179 | 190 | 174 | 180 | 182 | 189 | 182 | 199 | 174 | 184 | 179 | 194 | 179 | 190 | 180 |
↵* Data are continuations of subsequent set of data.
Calculations for control subject 209:
Hepatic bile area = Number of pixels × pixel area.
Initial hepatic bile area = 5 × 10.95 = 55 mm2.
Maximum hepatic bile area = 233 × 10.95 = 2,551 mm2.
Net hepatic bile transit area = 2,551 − 55 = 2,496 mm2.
Hepatic bile transit time = 34 − 11 = 23 min.
Hepatic bile transit rate = 2,496/23 = 109 mm2/min.
Adjusted transit rate = 108 × 1,000/2,551 = 42 mm2/min/1,000 mm2.
Note that minimum number of hepatic bile pixels in frames between 51 and 60 min was 233 at 53 min. However, this low number was seen first at 34 min, indicating that gallbladder complete filling with radiolabeled hepatic bile occurred earlier at this time interval.