TABLE 1

Hemodynamic Parameters

Parameter	Baseline	Stenosis	Arbutamine (ng/kg/min)
Parameter	Baseline	Stenosis				5	10	50	100	250
Heart rate (bpm)	124 ± 5	123 ± 5	133 ± 5*	141 ± 5*	176 ± 7*	192 ± 7*	208 ± 9*
MAP (mm Hg)	113 ± 5	114 ± 6	112 ± 6	111 ± 6	102 ± 6	98 ± 7	86 ± 7^†
LAP (mm Hg)	6.3 ± 0.4	7.1 ± 0.4	6.1 ± 0.3	6.0 ± 0.33	6.4 ± 0.5	6.4 ± 0.5	6.8 ± 0.6
dP/dt (mm Hg/s)	2,188 ± 141	2,201 ± 111	2,489 ± 199	2,921 ± 277^†	4,063 ± 258*	4,452 ± 238*	4,372 ± 453*
LAD flow (mL/min)	23 ± 3	18 ± 2	19 ± 2^†	20 ± 2	20 ± 2^†	21 ± 2	17 ± 2
LCX flow (mL/min)	31 ± 4	31 ± 5	36 ± 6*	41 ± 7*	58 ± 9*	60 ± 9*	68 ± 11*

↵* P < 0.001 vs. stenosis.
↵^† P < 0.05 vs. stenosis.
MAP = mean arterial pressure; LAP = left atrial pressure.
Values are expressed as mean ± SEM.