Comparison of Detectability of Bone Metastases Between 99mTc-HMDP and 99mTc-MIBI Scans in Relation to Skeletal Sites
| Site | No. of metastases | 99mTc-HMDP(+), 99mTc-MIBI(−) | 99mTc-HMDP(−), 99mTc-MIBI(+) | 99mTc-HMDP(+), 99mTc-MIBI(+) | 99mTc-HMDP(+)* | 99mTc-MIBI(+)* | 99mTc-HMDP vs. 99mTc-MIBI |
|---|---|---|---|---|---|---|---|
| Rib | 57 | 15 | 12 | 30 | 45 (78.9) | 42 (73.7) | NS |
| Thoracic spine | 33 | 8 | 6 | 19 | 27 (81.8) | 25 (75.8) | NS |
| Lumbar spine | 23 | 9 | 4 | 10 | 19 (82.6) | 14 (60.9) | NS |
| Sternum | 18 | 0 | 4 | 14 | 14 (77.8) | 18 (100) | NS |
| Pelvis | 62 | 12 | 11 | 39 | 51 (82.3) | 50 (80.6) | NS |
| Humerus | 22 | 1 | 11 | 10 | 11 (50.0) | 21 (95.5) | P < 0.005 |
| Femur | 98 | 1 | 63 | 34 | 35 (35.7) | 97 (99.0) | P < 0.005 |
| Other | 21 | 4 | 5 | 12 | 16 (76.2) | 17 (81.0) | NS |
| Total | 334 | 50 | 116 | 168 | 218 (65.3) | 284 (85.0) | P < 0.005 |
↵* Value in parentheses is percentage.
99mTc-HMDP(+) = 99mTc-HMDP positive; 99mTc-HMDP(−) = 99mTc-HMDP negative; 99mTc-MIBI(+) = 99mTc-MIBI positive; 99mTc-MIBI(−) = 99mTc-MIBI negative; NS = not significant.