Results for Patients with Cognitive Impairment
| Patient no. | Sex | Age at time of SPECT (y) | Working diagnosis | Time difference between SPECT and MRI (d) | SPECT result (visual) | MRI | Neuropsychology | Mini-Mental State Examination |
|---|---|---|---|---|---|---|---|---|
| 1 | M | 75.1 | AD | 1 | ↓ bil temp, R par | CSC atrophy, multiple WML | mem | 12 |
| 2 | F | 74.8 | FTD | 1 | ↓ bil front, R lat temp | temp/hippocampal atrophy, some WML | visuospat, exec | 17 |
| 3 | F | 68.5 | AD | 1 | ↓ bil cereb | CSC and cereb atrophy, multiple WML | mem, exec | 19 |
| 4 | M | 83.6 | AD | 1 | ↓ bil front, L lat temp | front-par-occ hemosiderin, ischemic lesions basal ganglia | mem | 16 |
| 5 | F | 76.5 | AD | 1 | ↓ L front, R par, R head caud | CSC atrophy | mem | 22 |
| 6 | M | 70.9 | MID | 0 | ↓ R occ | Infarction R cerebri media, generalized atrophy, multiple WML | visuospat mem | 18 |
| 7 | M | 61.2 | MID | 1 | No defects | temp-par atrophy, ischemic lesion R posterior watershed area, stem infarct | No deficit | 24 |
| 8 | M | 85.3 | AD | 0 | ↓ R front, L striat, R head caud | CSC and cereb atrophy, multiple WML basal ganglia; periventricular leukoaraiosis | visuospat, exec, mem, verbal | 10 |
| 9 | F | 79.2 | AD | 0 | ↓ R front, R par | CSC and cereb atrophy, multiple WML basal ganglia; periventricular leukoaraiosis | No deficit | 23 |
| 10 | F | 83.8 | AD | 0 | ↓ R thal, R head caud | Mild atrophy, moderate multiple WML; periventricular leukoaraiosis | NA | 21 |
| 11 | F | 80.1 | AD | 0 | No defects | Mild atrophy, moderate multiple WML; periventricular leukoaraiosis | (Visual) mem, visuospat | 23 |
| 12 | F | 84.5 | AD | 3 | ↓ bil front, R lat temp, bil head caud | CSC atrophy, some WML | (Visual) mem, visuospat, exec | 9 |
| 13 | F | 73.3 | AD | NA | ↓ L front, L cereb | NA | visuospat | 23 |
| 14 | M | 55.4 | AD | 1 | ↓ R lat temp, R par | Mild atrophy, mild WML | visuospat | 20 |
| 15 | M | 75.7 | AD | NA | ↓ R front, L lat temp, L par | NA | visuospat, exec | 22 |
AD = Alzheimer’s disease; bil = bilateral; temp = temporal; par = parietal; CSC = corticosubcortical; WML = white matter lesion; mem = memory; FTD = frontotemporal dementia; front = frontal; lat = lateral; visuospat = visuospatial; exec = executive; cereb = cerebellum; occ = occipital; head caud = head caudate; MID = multiinfarct dementia; striat = striatum; NA = not available.