TABLE 1

PET and Histopathology Scores

PET scores (lung area)Histopathology scores (severity/distribution)
Months after challengeLung region
1245RaRcRdazLaLcLd
1. Control00000000
2. Control000000—0
3. Control00000000
4. Silicotic2.5 (R)2/32/42/32/2—02/3
2.5 (L)
5. Silicotic3.5 (R)02/3—02/3—2/3
2.5 (L)
6. Silicotic4 (R)2/32/42/3——0—
7. Silicotic3.5 (M)—2/32/42/5000
8. Silicotic4 (L)——000—2/4
9. Control—00000000
10. Control000000000
11. Control0000000—0
12. Silicotic2.5 (R)3 (R)2/32/32/33/500—
13. Silicotic2.5 (R)2.5 (L)2/4—2/3—0—2/3
1.5 (L)
14. Silicotic2.5 (L)4.5 (L)2/3—————3/4
2.5 (M)
15. Silicotic3.5 (L)4.5 (L)0000003/4
16. Silicotic2.5 (R)3.5 (L)2/32/3002/32/42/4
17. Silicotic3.5 (R)3.5 (L)02/302/4000
3.5 (L)
18. Control00—00000000
19. Control2.5 (R)3 (R)—00000000
20. Control0001.5 (M)0000000
21. Control01.5 (R)00000000
22. Silicotic3.5 (R)3.5 (R)1.5 (R)3.5 (R)2/32/3—3/5000
3.5 (M)3.5 (M)3.5 (M)
23. Silicotic3 (R)4 (R)4.5 (R)4 (R)3/33/43/4—000
3 (M)
24. Silicotic3.5 (R)3 (R)3.5 (R)3 (R)2/32/32/32/32/300
25. Silicotic4.5 (L)3.5 (L)4.5 (L)3.5 (L)02/32/30003/3
1.5 (R)
26. Silicotic04.5 (L)4.5 (L)00000—3/4
27. Silicotic3 (R)2.5 (R)3.5 (R)—2/32/32/300—
28. Silicotic1.5 (M)2.5 (L)1.5 (R)2/32/3002/32/33/3
2 (R)

  • For PET scores, 0 indicates all lung regions were 0; a dash indicates some regions were >0 but none were >1. For histopathology scores, a dash indicates either severity or distribution was >0 but ≤1.