TABLE 1

Binding Properties of NT-VIII in HT-29 Cells

PeptideIC50* (nmol/L)Kd (nmol/L)
NT0.9†1.6
NT-VIII21.11.8
natRe(CO)3NT-VIII7.3—

  • ↵* Displacement of 125I-NT binding.

  • ↵† Value for NT(8–13).

  • Data are from 2–3 experiments in triplicate. Kd was determined with 125I-NT and 99mTc(CO)3NT-VIII.