Radiation Dose per Administered Activity to Surface of Urinary Bladder Wall as Provided by Dynamic Bladder Model
| Initial bladder volume (mL) | Initial void time (min) | |||||||
|---|---|---|---|---|---|---|---|---|
| 20 | 60 | 120 | 180 | |||||
| Mean | Range | Mean | Range | Mean | Range | Mean | Range | |
| 10 | 0.17 | 0.10–0.40 | 0.16 | 0.09–0.36 | 0.17 | 0.10–0.38 | 0.18 | 0.11–0.41 |
| 50 | 0.13 | 0.07–0.32 | 0.11 | 0.06–0.25 | 0.11 | 0.06–0.25 | 0.12 | 0.07–0.27 |
| 200 | 0.12 | 0.06–0.29 | 0.08 | 0.04–0.17 | 0.07 | 0.03–0.14 | 0.07 | 0.04–0.14 |
| 500 | 0.11 | 0.06–0.28 | 0.07 | 0.03–0.14 | 0.05 | 0.02–0.09 | 0.04 | 0.02–0.08 |
Data show mean and range (in mGy/MBq) of doses for the 13 studies from investigation by Hays and Segall (2), as function of selected initial bladder volumes and initial void times. Data indicate variability between individual studies and importance of initial bladder volume and timing of initial void. Calculations assumed day/night bladder filling rate of 1.0/0.5 mL/min, with administration of radiopharmaceutical at 9:00 am. Voiding schedule was every 3 h until midnight, with 6-h nighttime gap between midnight and 6:00 am. Dynamic bladder model is that described in Thomas et al. (4).