TABLE 1

CAG Repeat Numbers, Striatal Binding, and P/C of ^99mTc-TRODAT-1 in 5 aMJD Carriers, 10 MJD Patients, and 10 Healthy Control Subjects

Participant type	No.	Abnormal CAG no.	Striatum		P/C
Participant type	No.	Abnormal CAG no.	Right	Left	Right	Left
aMJD	1*	79	2.08	1.97	0.74	0.57
	2*	72	1.83	1.81	0.73	0.69
	3*	68	2.17	2.22	0.75	0.77
	4^†	72	2.07	1.92	0.70	0.61
	5^†	72	1.79	1.82	0.74	0.66
Mean ± SD		72.6 ± 4.0^‡	1.99 ± 0.17^‡	1.95 ± 0.17^‡	0.73 ± 0.02	0.66 ± 0.08
MJD	1^†	75	1.73	1.75	0.66	0.72
	2	82	1.44	1.55	0.71	0.74
	3	79	1.50	1.63	0.59	0.75
	4	85	1.43	1.53	0.67	0.63
	5	80	1.69	1.65	0.63	0.62
	6	77	1.53	1.45	0.67	0.60
	7	79	1.53	1.43	0.89	0.83
	8	80	1.40	1.56	0.63	0.72
	9	77	1.56	1.56	0.62	0.67
	10	72	1.94	1.89	0.72	0.74
Mean ± SD		78.6 ± 2.5^‡	1.58 ± 0.17^‡	1.60 ± 0.14^‡	0.68 ± 0.06	0.70 ± 0.07
Control	1*		2.36	2.36	0.87	0.82
	2*		2.49	2.43	0.73	0.75
	3		2.81	2.78	0.84	0.87
	4		2.80	3.00	0.78	0.83
	5		3.02	3.09	0.73	0.78
	6		2.74	2.64	0.89	0.85
	7		3.26	3.09	0.81	0.82
	8		2.85	2.73	0.76	0.76
	9		2.60	2.80	0.70	0.73
	10		2.94	2.79	0.79	0.81
Mean ± SD			2.79 ± 0.26	2.77 ± 0.25	0.79 ± 0.06	0.80 ± 0.05

↵* Members of same family.
↵† Members of same family.
↵‡ Significant difference between aMJD and MJD (P < 0.05) using generalized estimating equations approach.
All comparisons between control and aMJD and between control and MJD are significant (P < 0.001).