Structure–Function Correlations
| Mebrofenin parameter | Liver copper | Histology grade | Stimulated bile copper excretion | Serum ALT |
|---|---|---|---|---|
| Tpeak | 0.84 (0.002) | 0.86 (<0.001) | NA | 0.62 (0.04) |
| T1/2 peak | 0.88 (<0.001) | 0.76 (<0.001) | NA | 0.68 (0.02) |
| Mebrofenin retention at 20 min (% Tpeak) | 0.91 (<0.001) | 0.8 (<0.001) | −0.6 (0.02) | 0.71 (0.01) |
| Mebrofenin retention at 60 min (cpm/g) | 0.86 (0.002) | 0.67 (0.02) | −0.59 (0.04) | 0.72 (0.02) |
NA = not applicable.
Data are correlation coefficients, with probability values in parentheses.