Histologic Grading of Hepatic Lesions
| Histologic criteria | Severity of lesion | Nuclei affected (% total) | Score |
|---|---|---|---|
| Polyploidy | Mild | 0 –10 | 1 |
| Moderate | 11 –25 | 2 | |
| Marked | 26 –50 | 3 | |
| Severe | >50 | 4 | |
| Steatosis | Mild | 0 –10 | 1 |
| Moderate | 11 –25 | 2 | |
| Marked | 26 –50 | 3 | |
| Severe | >50 | 4 | |
| Apoptosis* | Absent | 0 | 0 |
| Mild | 1 –5 | 2 | |
| Marked | >5 | 4 | |
| Mitosis | Absent | — | 0 |
| Present | — | 1 |
↵* Number of apoptotic bodies per high-power field.