Uptake (% Dose kg/100 g) of 18F-FCH in Tissues of Tumor-Bearing and Control Mice (male BALB/c nu/nu)
| Tissue | PC-3 | MCF7 60 min (n = 5) | Control | |||
|---|---|---|---|---|---|---|
| 10 min (n = 5) | 30 min (n = 3) | 60 min (n = 5) | 60 min (n = 5) | 10 h (n = 6) | ||
| Tumor | 3.6 ± 0.6 | 7.1 ± 2.1 | 7.9 ± 5.0 | 4.3 ± 1.5 | — | — |
| Blood | 2.7 ± 0.9 | 3.3 ± 0.2 | 1.5 ± 0.6 | 2.3 ± 0.5 | 1.1 ± 0.3 | 1.5 ± 0.4 |
| Heart | 15.5 ± 5.9 | 13.2 ± 2.6 | 12.7 ± 3.2 | 17.2 ± 2.5 | 18.0 ± 8.0 | 23.5 ± 5.1 |
| Brain | 0.8 ± 0.3 | 1.0 ± 0.2 | 0.8 ± 0.1 | 1.3 ± 0.4 | 1.4 ± 0.6 | 1.7 ± 0.4 |
| Lung | 18.0 ± 5.3 | 17.1 ± 1.4 | 21 ± 4.4 | 22.5 ± 2.8 | 30.2 ± 10.9 | 28.6 ± 5.8 |
| Liver | 50.7 ± 15.3 | 56.7 ± 13.2 | 58.4 ± 40.6 | 37.8 ± 13.0 | 24.5 ± 13.4 | 26.6 ± 9.8 |
| Kidney | 127.7 ± 27.6 | 116 ± 17.0 | 94.3 ± 31.0 | 99.2 ± 25.4 | 75.6 ± 25.7 | 90.6 ± 17.5 |
| Skeletal muscle | 4.4 ± 1.8 | 1.1 ± 1.0 | 4.1 ± 0.6 | 4.1 ± 0.9 | 2.2 ± 1.0 | 2.9 ± 1.0 |