Independent variable | Dependent variable | Slope | Intercept (mL/g/min) | r | P of r |
---|---|---|---|---|---|
KGLUCOSE | KPET-GLUCOSE | 0.77 ± 0.05 | 0.03 ± 0.01 | 0.97 | <0.0001 |
KGLUCOSE | KPET-18F-FDG-PATLAK | 0.50 ± 0.09* | 0.04 ± 0.02 | 0.78† | <0.0001 |
KGLUCOSE | KPET-18F-FDG-NE | 0.75 ± 0.12 | 0.08 ± 0.02 | 0.82† | <0.0001 |
KGLUCOSE | KPET-18F-FDG-E | 0.52 ± 0.09* | 0.004 ± 0.015 | 0.81† | <0.0001 |
↵* P < 0.05 vs. KPET-GLUCOSE slope.
↵† P < 0.05 vs. KPET-GLUCOSE correlation coefficient (r).
KGLUCOSE = glucose uptake measured directly from plasma glucose levels by Fick method; KPET-GLUCOSE = glucose uptake measured by PET and kinetic modeling of 1-11C-glucose; KPET-18F-FDG-PATLAK = 18F-FDG uptake measured by PET and Patlak method; KPET-18F-FDG-NE = 18F-FDG uptake measured by PET and kinetic modeling of 18F-FDG after assuming that 18F-FDG egress is negligible; KPET-18F-FDG-E = 18F-FDG uptake measured by PET and kinetic modeling of 18F-FDG after assuming that 18F-FDG egress is not negligible.
Data in Slope and Intercept columns represent estimated values from linear regression analysis and their corresponding SEs.