Whole-Body 18F-FDG PET Scan Results
| Disease status | Result of baseline study | Result of follow-up study |
|---|---|---|
| MGUS | 14/14 (100%) negative; followed 3–43+ mo | In 1/14 (7%), myeloma developed at 8 mo; in 1 patient, focal plasmacytoma with amyloid developed* |
| Active myeloma | 16/16 (100%) positive; 4/16 (25%) had negative radiography results but multiple focal lesions on scan | In 1 patient, disease was upstaged from stage I to III: Multiple new disease sites were identified |
| 4/16 (25%) had extramedullary disease | Poor outcome with extramedullary disease | |
| Remission | In 6/10 (60%), new lesions developed over 6–42+ mo | Local irradiation used for focal relapse; nonsecretory relapse detected and treated |
| Relapse | 21/26 (81%) had new sites of disease | Anatomic distribution of lesions documented |
| 6/26 (23%) had extramedullary disease | Very poor survival with extramedullary disease: median, 7 mo |