TABLE 2

PET Data

Pig no.	Age (y)	f (mL/[min · cm³])	E	K₁ (mL/[min · cm³])	k₂ (min⁻¹)	k₃ (min⁻¹)	k₄ (min⁻¹)	BV (mL/cm³)	K_i (mL/[min · cm³])	K_flux (μmol/[min · L])	K_pat (mL/[min · cm³])	K_pat120 (mL/[min · cm³])
1	6.7	0.075 ± 0.017	0.95 ± 0.32	0.068 ± 0.015	0.096 ± 0.108	0.113 ± 0.089	0.005 ± 0.003	0.034 ± 0.017	0.040 ± 0.004	0.610 ± 0.058	0.036 ± 0.002	0.032 ± 0.002
2	3.1	0.132 ± 0.039	0.82 ± 0.27	0.100 ± 0.016	0.025 ± 0.012	0.037 ± 0.018	0.003 ± 0.002	0.058 ± 0.010	0.058 ± 0.003	1.052 ± 0.058	0.055 ± 0.007	0.032 ± 0.002
3	2.2	0.196 ± 0.017	0.73 ± 0.08	0.142 ± 0.006	0.038 ± 0.013	0.044 ± 0.017	0.004 ± 0.003	0.030 ± 0.029	0.076 ± 0.003	1.031 ± 0.046	0.073 ± 0.002	0.051 ± 0.005
4	3.3	0.149 ± 0.058	1.00 ± 0.06	0.131 ± 0.014	0.251 ± 0.171	0.292 ± 0.159	0.008 ± 0.001	0.024 ± 0.010	0.073 ± 0.005	1.568 ± 0.112	0.061 ± 0.006	0.052 ± 0.004
5	2.5	0.087 ± 0.032	0.81 ± 0.01	0.069 ± 0.018	0.053 ± 0.041	0.134 ± 0.046	0.021 ± 0.048	0.040 ± 0.021	0.049 ± 0.003	0.780 ± 0.046	0.050 ± 0.006	0.042 ± 0.005
6	3.9	0.122 ± 0.019	0.88 ± 0.11	0.106 ± 0.009	0.046 ± 0.051	0.106 ± 0.127	0.008 ± 0.004	0.032 ± 0.025	0.072 ± 0.002	1.736 ± 0.058	0.065 ± 0.008	0.058 ± 0.008
7	6.7	0.149 ± 0.038	0.90 ± 0.23	0.126 ± 0.010	0.049 ± 0.032	0.076 ± 0.045	0.005 ± 0.004	0.008 ± 0.010	0.076 ± 0.008	1.255 ± 0.126	0.074 ± 0.006	0.064 ± 0.003
8	1.5	0.106 ± 0.014	0.88 ± 0.17	0.092 ± 0.011	0.050 ± 0.041	0.088 ± 0.060	0.006 ± 0.003	0.018 ± 0.005	0.060 ± 0.003	0.997 ± 0.047	0.055 ± 0.003	0.050 ± 0.003
9	1.6	0.126 ± 0.037	0.97 ± 0.36	0.112 ± 0.014	0.127 ± 0.119	0.167 ± 0.124	0.009 ± 0.006	0.026 ± 0.024	0.066 ± 0.006	1.360 ± 0.133	0.058 ± 0.005	0.052 ± 0.005
All pigs	3.5 ± 2.0	0.127 ± 0.036	0.89 ± 0.10	0.105 ± 0.026	0.081 ± 0.071	0.117 ± 0.077	0.008 ± 0.005	0.030 ± 0.014	0.063 ± 0.012	1.154 ± 0.360	0.058 ± 0.011	0.050 ± 0.009

Data are for 6 vertebral bodies of each mini pig. In addition, estimates of f and E derived from K₁ values using permeability surface product of 0.25 min⁻¹ are given. [¹⁸F]fluoride ion influx rate was also estimated with Patlak graphic approach using 2 different intervals (20–60 and 40–120 min).