TABLE 2

Added Value of TET for Image Interpretation and Clinical Management of 11 Patients with Endocrine Neoplasms

Patient no.	Sex	Age (y)	Tumor type	Radiopharmaceutical	NM results	TET results	Added value of TET for image interpretation	Clinical value of TET
1	M	44	Gastrinoma	¹¹¹In-octreotide	Increased focal uptake in upper abdomen	Uptake in retroperitoneal, normal-sized lymph node, at level of renal vein	Localization of lesion	Better planning of surgical approach
2	M	41	Recurrent NE tumor	¹¹¹In-octreotide	Two foci of increased uptake in midabdomen	Uptake in retroperitoneum, paravertebral; detection of bone involvement of T12 and L1 vertebrae	Localization of lesions, detection of bone involvement	Change in therapeutic approach (surgery canceled)
3	F	58	NE tumor	¹¹¹In-octreotide	Two foci of increased uptake in midabdomen	Two foci of uptake in pancreas	Localization of both lesions to pancreas, retrospective detection of second lesion on CT	Better planning of surgical approach
5	M	47	Carcinoid tumor	¹¹¹In-octreotide	Multiple abdominal lesions	Multiple hepatic lesions, no extrahepatic sites of uptake	Localization of lesions, exclusion of extrahepatic disease	Choice of therapeutic approach (chemoembolization)
7	M	40	Medullary thyroid carcinoma	¹¹¹In-octreotide	Increased uptake in lower neck and upper mediastinum	Uptake in upper L mediastinum and R clavicle	Localization of lesion, detection of bone involvement	Change in prognosis
14	F	81	Suspected parathyroid adenoma	^99mTc-sestamibi	Increased uptake in R upper mediastinum	Uptake in R paratracheal region extending posteriorly	Localization of ectopic adenoma	Better planning of surgical approach
15	F	70	Suspected parathyroid adenoma	^99mTc-sestamibi	Increased uptake in R upper mediastinum	Uptake in R upper anterior mediastinum	Localization of ectopic adenoma	Better planning of surgical approach
19	M	46	Papillary thyroid carcinoma	¹³¹I	Increased uptake in lungs and L upper thorax	Foci of uptake in both lungs and L coracoid	Localization of lesion, detection of bone involvement	Change in prognosis
21	F	68	Papillary thyroid carcinoma	¹³¹I	Increased uptake in upper mediastinum	Focal uptake in sternum only	Localization of lesion, detection of bone involvement	Change in therapeutic approach (referral for surgery)
23	F	68	Suspected pheochromocytoma	¹²³I-MIBG	Increased uptake in R posterior midabdomen	Focal uptake in R ureter	Localization of physiologic uptake	Exclusion of disease
26	M	59	Suspected aldosteronoma	⁷⁵Se-cholesterol	Increased uptake in L abdomen, suspected additional uptake in R abdomen	Focal uptake in L adrenal (tumor), focal uptake in R colon (physiologic)	Localization of lesion to L adrenal only, localization of physiologic uptake	Exclusion of disease

NM = nuclear medicine; NE = neuroendocrine; CT = high-resolution, contrast-enhanced conventional CT.