Calculated BPs for Several Regions Using 5 Methods
| Region | Method* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| FC | 0.64 ± 0.06 | 0.57 ± 0.08 | 0.64 ± 0.05 | 0.49 ± 0.05 | 0.91 ± 0.40 |
| CC | 0.83 ± 0.09 | 0.71 ± 0.09 | 0.84 ± 0.12 | 0.65 ± 0.11 | 1.23 ± 0.57 |
| INS | 1.32 ± 0.24 | 1.19 ± 0.26 | 1.29 ± 0.21 | 1.18 ± 0.21 | 1.89 ± 1.06 |
| LTC | 1.19 ± 0.11 | 1.05 ± 0.14 | 1.16 ± 0.13 | 1.08 ± 0.21 | 1.75 ± 0.47† |
| MTC | 2.02 ± 0.27 | 1.72 ± 0.27 | 1.92 ± 0.18 | 1.77 ± 0.23 | 3.24 ± 1.54† |
↵* Logan (22) analysis using metabolite-corrected arterial input (method 1), uncorrected arterial input (method 2), or cerebellar time–activity curve input (method 3); simplified reference tissue model (method 4) (28); and standard compartmental modeling (method 5).
↵† Significantly different (P < 0.05) compared with method 1.
FC = frontal cortex; CC = cingulate cortex; INS = insular cortex; LTC = lateral temporal cortex; MTC = medial temporal cortex.
Data are listed as mean ± SD (n = 6).